| dc.contributor.advisor | ATMAJA, WIDYAPRAMANA DWI | |
| dc.contributor.author | ARIMURTI, PRAMESTARI FAJAR | |
| dc.date.accessioned | 2017-08-18T02:48:27Z | |
| dc.date.available | 2017-08-18T02:48:27Z | |
| dc.date.issued | 2017-07-18 | |
| dc.identifier.uri | http://repository.umy.ac.id/handle/123456789/13048 | |
| dc.description | Background: Acrylic resin (polymethil methacrylate) was one of the material based on denture which frequently used in dentistry. The less cleaning of dentures may accumulated the growth of Candida albicans of plaque that contained in acrylic resin plate. Candida albicans was the cause of denture stomatitis on denture user. The phytochemical test showed Salacca zalacca extracts contained various active compounds such as flavonoids, tannins, saponins and alkaloids that could inhibit the growth of microorganisms.
Aim: The purpose of the study was to determine the effect of various concentrations of Salacca zalacca extracts on the growth of Candida albicans on acrylic resin plate.
Methods: The laboratory experiment used as the method of this study. There were twenty five acrylic resin samples were made with 10 mm diameter and 2 mm thick soaked in sterilized saliva for 1 hour and put into Candida albicans suspension for 24 hours. Samples divided into 5 treatments, then soaked with different concentration of 25%, 50%, 75%, 100% and sterile distilled water as control for 8 hours. Serial dilutions are needed after samples were taken. The colony of Candida albicans was counted after planted into saboraud agar and 48 hours of incubation.
Result: The result showed the significant differences of various concentrations of Salacca zalacca extracts on the growth of Candida albicans P=0,000 (p<0,05). The highest number of Candida albicans was in aquades and the lowest number of Candida albicans was in 100% concentration.
Conclusion: As the conclusion in results of this study there were effect of Salacca zalacca extracts concentrations of 25%, 50%, 75% and 100% on the growth of Candida albicans on acrylic resin plate. The lowest number of Candida albicans was in 100% concentration. | en_US |
| dc.description.abstract | Latar belakang: Resin akrilik (polymethil methacrylate) merupakan salah satu bahan basis gigi tiruan yang sering digunakan di kedokteran gigi. Pembersihan gigi tiruan yang kurang dapat memicu akumulasi pertumbuhan Candida albicans pada plak yang terdapat pada plat resin akrilik. Candida albicans merupakan penyebab denture stomatitis pada pengguna gigi tiruan. Hasil uji fitokimia ekstrak buah salak pondoh (Salacca zalacca) mengandung senyawa aktif flavonoid, tanin, saponin dan alkaloid yang dapat menghambat pertumbuhan mikroorganisme.
Tujuan penelitian: Untuk mengetahui pengaruh berbagai konsentrasi ekstrak buah salak pondoh (Salacca zalacca) terhadap pertumbuhan Candida albicans pada plat resin akrilik.
Metode penelitian: Metode yang digunakan pada penelitian ini adalah eksperimental laboratoris. Dua puluh lima sampel cakram resin akrilik diameter 10 mm dan tebal 2 mm direndam dalam saliva buatan selama 1 jam kemudian direndam dalam suspensi Candida albicans selama 24 jam. Sampel dibagi dalam 5 kelompok perlakuan lalu direndam dengan konsentrasi berbeda yaitu konsentrasi 25%, 50%, 75%, 100% dan aquades steril sebagai kontrol selama 8 jam. Sampel diambil dan dilakukan pengenceran seri. Jumlah koloni Candida albicans dihitung pada media Saboraoud setelah diinkubasi selama 48 jam. Data yang diperoleh dianalisis dengan one-way ANOVA dan dilanjutkan dengan uji Post hoc.
Hasil penelitian: Hasil penelitian menunjukkan terdapat perbedaan bermakna pada setiap konsentrasi ekstrak buah salak pondoh (Salacca zalacca) terhadap pertumbuhan jamur Candida albicans dengan p = 0,000 atau (p<0,005). Rerata angka jamur Candida albicans tertinggi pada aquades dan angka jamur Candida albicans terendah pada konsentrasi 100%.
Kesimpulan: Terdapat pengaruh ekstrak salak (Salacca zalacca) konsentrasi 25%, 50%, 75% dan 100% terhadap pertumbuhan Candida albicans pada plat resin akrilik. Penurunan jumlah jamur Candida albicans tertinggi pada konsentrasi 100%. | en_US |
| dc.publisher | FKIK UMY | en_US |
| dc.subject | Salak pondoh (Salacca zalacca), Candida albicans, Plat resin akrilik. Salacca zalacca, Candida albicans, acrylic resin. | en_US |
| dc.title | PENGARUH KONSENTRASI EKSTRAK BUAH SALAK PONDOH (Salacca zalacca) TERHADAP PERTUMBUHAN Candida albicans PADA PLAT RESIN AKRILIK | en_US |
| dc.type | Thesis
SKR
FKIK
264 | en_US |
