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dc.contributor.advisor
dc.contributor.authorPRIMASARI, MEILIA RIZKI
dc.date.accessioned2018-04-17T06:00:40Z
dc.date.available2018-04-17T06:00:40Z
dc.date.issued2017-06-10
dc.identifier.urihttp://repository.umy.ac.id/handle/123456789/18517
dc.descriptionObat nyamuk merupakan obat yang digunakan untuk membasmi nyamuk dalam suatu ruangan. Saat ini obat nyamuk yang beredar di pasaran sangat beragam. Misalnya Obat nyamuk spray yang mengandung zat toksik berbahaya yaitu pralethrin (0,1%), siflutrin (0,05%) dan d-Allethrin (0,57%) dan obat nyamuk one push yang mengandung zat toksik berbahaya yaitu transflutrin (21,3%). Penelitian ini bertujuan untuk mengetahui pengaruh obat nyamuk spray dan obat nyamuk one push terhadap diameter tubulus seminiferus dan jumlah sperma. Jenis penelitian ini adalah eksperimental murni dengan post-test only control group design. Subyek penelitian adalah 30 ekor tikus putih (Rattus norvegicus) dengan usia 2 bulan dan dibagi menjadi 5 kelompok yaitu kelompok kontrol (K), kelompok one push 5 menit (P1), kelompok one push 10 menit (P2), kelompok spray 5 menit (P3), dan kelompok spray 10 menit (P4). Pendedahan dilakukan selama 60 hari. Pada hari ke-61 tikus dibedah untuk diambil testisnya, kemudian dibuat preparat histologi. Data diambil, kemudian diukur diameter tubulus seminiferus dan dihitung jumlah sperma. Analisis Kruskal-Wallis menunjukkan hasil rata-rata diameter tubulus seminiferuskelompokK(237.985±18.3707);P1(218.578±14.1157);P2(218.863±14.1157);P3(216.994±16.5588); P4(207.450±32.1342) dengan p=0,000 (signifikan). Analisis One-Way ANOVA menunjukkan hasil rata-rata jumlah sperma kelompok K(5,796±1,297);P1(3,777±1,328);P2(3,648±1,041);P3(3,940±1,503);P4(2,015±0,782) dengan p=0,000 (signifikan). Dapat disimpulkan bahwa pendedahan obat nyamuk spray dan obat nyamuk one push dapat mempengaruhi diameter tubulus seminiferus dan jumlah sperma.en_US
dc.description.abstractBackground: Mosquito Repellent is a drug that used to eradicate the mosquitoes in a room. nowadays, there are many variation of a mosquito repellent that distribute in the market.as example is a spray mosquito repellent that contain a toxic subtances like pralethrin (0,1%), sifultrin (0,05%) and d-Allethrin (0,57%). In the one push mosquito repellent contain a toxic subtance called transflutrin (21,3%). The goal of this study is to analyze the effect of spray mosquito repellent and one push mosquito repellent against the diameter of tubulus seminiferus and the amount of sperm in rat (rattus norvegicus). Methods: the design of this study is laboratoric experimental with post-test only control group design. This study use 30 rat (Rattus novergicus) with the age of 2 months and divided into 5 group. The data is taken, and then the diamater of tubulus seminiferus is measured and the amount of sperm is calculated. Result: the result of one-way ANOVA statictic show that there is meaningful difference in the amount of sperm (p<0,05) with the result of the 10 minutes spray group (P4) that have lowest amount of sperm. The Kruskal-Wallis result show that there is meaningful differences in diameter of tubulus seminiferus (p<0,05) with the result of 10 minutes spray group (P4) that have smallest diameter. Conclusion: the differenciation of spray mosquito repellent and one push mosquito repellent can affect the diameter of tubulus seminiferus and the amount of sperm.en_US
dc.publisherFKIK UMYen_US
dc.subjectspray, one push, diameter tubulus seminiferus, jumlah sperma. spray mosquito repellent, one push mosquito repellent, tubulus seminiferus diameters, sperm’s amounten_US
dc.titlePENGARUH OBAT NYAMUK SPRAY DAN OBAT NYAMUK ONE PUSH TERHADAP DIAMETER TUBULUS SEMINIFERUS DAN JUMLAH SPERMA PADA TIKUS PUTIH (Rattus norvegicus)en_US
dc.typeThesis SKR FKIK 475en_US


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