| dc.contributor.author | ORBAYINAH, SALMAH | |
| dc.date.accessioned | 2016-09-15T07:15:32Z | |
| dc.date.available | 2016-09-15T07:15:32Z | |
| dc.date.issued | 2008-10 | |
| dc.identifier.uri | http://repository.umy.ac.id/handle/123456789/1996 | |
| dc.description | Salmah Orbayinah, Adhita Kartyanto, Efikasi Binahong ..............................
90
Hasil penelitian menunjukkan rata-rata kadar ALP serum pada kelompok kontrol sebelum
dan sesudah perlakuan adalah 95,94
+1,52 IU/l dan 110,15
+1,07 IU/l; pada kelompok perlakuan
adalah 92,65
+3,05 IU/l dan 92,91
+0,68 IU/l.
Paired T-test
menunjukkan perbedaan signifikan
sebelum dan sesudah perlakuan (p<0,05).
Independent T-test
menunjukkan perbedaan signifikan
(p<0,05) peningkatan ALP sebelum dan sesudah perlakuan pada kedua kelompok dimana kadar
ALP pada kelompok perlakuan lebih rendah daripada kelompok kontrol. Disimpulkan bahwa
pemberian jus daun Binahong (
Anredera cordifolia
(Ten.) Steenis) 329,21 mg setiap hari dapat
meningkatkan efek hepatoprotektif dengan menjaga kadar normal ALP pada tikus putih galur
Wistar | en_US |
| dc.description.abstract | Role of Binahong (Anredera cordifolia (Ten.) Steenis) leaves as hepatoprotector and
antioxidant was identified on CCl
4
– induced white rats.
Unrandomized control trial method was used in this study. Ten male Wistar white rats
with 200 – 250 gr of body weight were divided into two groups. Group I as a control group
was treated with standard food and 1 ml aquadest orally for 12 days. Group II as a treatment
group was given standar food and daily single dose pretreatment of Binahong (Anredera
cordifolia (Ten.) Steenis) leaves juice 289,8 mg/200 gr of body weight for 12 days. Carbon
tetrachloride (1 ml/kg body weight, i.p.) injected into rats in the day 13
th
to induce liver cells
damage. ALP test used ALP KIT reagent had been done twice, 1
st
day and 14
th
day.
The result shows mean of ALP level before and after treatment in control group were
95,94
+1,52 and 110,15
+1,07; in treatment group were 92,65
+3,05 and 92,91
+0,68. Paired
T-test shown significant difference before and after treatment (p<0,05). Independent T test
shown a significant difference ALP increasing between two group, while ALP serum level in
treatment group lower than control group. This study proved that Binahong (Anredera cordifolia
(Ten.) Steenis) leafs juice 289,8 ml / 200gr body weight each day could decrease hepatotoxicity
effect of carbon tetrachloride by maintain normal level of ALP in white rats Wistar strain | en_US |
| dc.description.sponsorship | FKIK UMY | en_US |
| dc.publisher | Mutiara Medika UMY | en_US |
| dc.relation.ispartofseries | Edisi Khusus Vol. 8 No. 2: 89 - 95; | |
| dc.source | Mutiara Medika
Edisi Khusus Vol. 8 No. 2: 89 - 95, Oktober 2008 | |
| dc.subject | antioxidant, alkaline phosphatase level, Anredera cordifolia (Ten.) Steenis, carbon tetrachloride | en_US |
| dc.title | EFIKASI BINAHONG ( ANREDERA CORDIFOLIA (TENORE) STEENIS) TERHADAP KADAR ALKALINE PHOSPHATASE | en_US |
