dc.contributor.advisor | MEDAWATI, ANA | |
dc.contributor.author | SAHAR, FADLAN HI | |
dc.date.accessioned | 2019-04-15T02:22:54Z | |
dc.date.available | 2019-04-15T02:22:54Z | |
dc.date.issued | 2019-02-08 | |
dc.identifier.uri | http://repository.umy.ac.id/handle/123456789/26055 | |
dc.description | Latar Belakang: Physalis adalah tanaman herbal dari family solananceae dan
memiliki 100 spesies salah satunya Physalis angulata L. yang lebih dikenal di
Indonesia dengan sebutan ceplukan atau ciplukan. Physalis angulata L.
Mengandung senyawa-senyawa aktif yang antara lain Flavonoid, polifenol,
Physalin B dan chlorogenikacid sebagai antibiotik. Streptococcus mutans
menghasilkan senyawa asam yang dapat menyebabkan gigi terdemineralisasi
sehingga kekuatan gigi menjadi berkurang dan dapat menjadi masalah
dikemudian hari
Tujuan Penelitian: Untuk mengetahui pengaruh daya antibakteri ekstrak etanol
daun ciplukan (Physalis angulata L.) terhadap bakteri Streptococcus mutans
Desain: Eksperimental laboratorium. Menggunakan ekstrak etanol daun ciplukan
(Physalis angulata L.) dengan konsentrasi 100%,50%, 25%, 12.5%, 6.25%,
3.13%, 1.56%, 0.78%, 0.39% dan 0.2%. Bakteri uji yang digunakan adalah
Streptococcus mutans. Pembacaan hasil penelitian dengan mengukur KHM dan
KBM
Hasil: Hasil penelitian menunjukkan kadar hambat minimum (KHM) antibakteri
ekstrak etanol daun ciplukan (Physalis angulata L.) terhadap bakteri
Streptococcus mutans pada konsentrasi 0,78% dan kadar bunuh minimum (KBM)
pada konsentrasi 1,56%.
Kesimpulan: Ekstrak etanol daun ciplukan (Physalis angulata L.) memiliki
kemampuan daya antibakteri terhadap bakteri Streptococcus mutans. | en_US |
dc.description.abstract | Background: Physalis is the herb of the family Solananceae and has 100 species
of one Physalis angulata L. Commonly known in Indonesia as ceplukan or
ciplukan. Physalis angulata L. Contains active compounds that include
flavonoids, polyphenols, Physalin B and chlorogenikacid as antibiotic.
Streptococcus mutans produces acid compounds that can cause demineralized
teeth so that the strength of teeth is reduced and can be problematic in the future
Objective: To determine the effect of antibacterial activity of ethanol extract of
the leaves ciplukan (Physalis angulata L.) against Streptococcus mutans
Design: Experimental laboratory. Using ethanol extract of the leaves ciplukan
(Physalis angulata L.) with a concentration of 100%, 50%, 25%, 12.5%, 6:25%,%
3:13, 1:56%, 0.78%, 12:39% and 0.2%. test bacteria used were Streptococcus
mutans diluted with BHI liquid medium so that the concentration becomes
106CFU /ml. The reading of the results by measuring the MIC and MBC
Result: The results showed the minimum inhibitory concentration (MIC) at a
concentration of 0.78% and a minimum baktercidal concentration (MBC) at a
concentration of 1,56%.
Conclusion: The ethanol extract of leaves ciplukan (Physalis angulata L.) has the
ability antibacterial power against Streptococcus mutans with MIC concentration
of 0.78% and MBC concentrations of 1.56%. | en_US |
dc.publisher | FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS MUHAMMADIYAH YOGYAKARTA | en_US |
dc.subject | S. mutans, Antibacterial Power, MIC, MBC, Ciplukan Leaf, Physalis angulata L. | en_US |
dc.title | PENGARUH DAYA ANTIBAKTERI EKSTRAK ETANOL DAUN CIPLUKAN (Physalis angulata L.) TERHADAP BAKTERI Streptococcus mutans (In Vitro) | en_US |
dc.type | Thesis
SKR
FKIK
055 | en_US |