| dc.description.abstract | Snail mucin has been widely known to contain agents with wound healing properties. A preliminary research with regard to the potential to manufacture composite nanofibrous membranes of polyvinylalcohol(PVA)andsnailmucin(SM)bytheelectrospinningtechniqueforwounddressingapplications has been conducted. The effect of SM concentration on the morphology and tensile properties of PVA/SM nanomembranehasbeeninvestigated. ThePVA/SMsolutionswithvariousconcentrationofSM(0%,2%,4%, dan 6%)(w/v) were electrospun at the optimized process parameters. The morphology nanofiber membranes wasobservedbyscanningelectronmicroscopyandtheaveragediametersofpreparednanofiberswasdetermined byimageanalysis technique. The tensiletest was conducted to examine the tensile propertiesofthe nanofiber membranes being prepared according to ASTM D882. The PVA/SM nanofibre membrane possessing the tensile strength and tensile strain ranging between 3.48-5.37 MPa and 101.25- 157.13 %, respectively were successfullyfabricated. Themembraneof10%(w/v)PVA/2%(w/v)SMachievedthehighestvaluesoftensile strength.Thisphenomenon hasbeenassociatedtothe uniformityoffiber size diameterdistribution withinthe membranes. It was expected that further optimization of the processing would allow development of the tensile properties compatibility requirement with this being the subject of future work by the authors. | en_US |
