Discourse about halal lifestyle is not only booming in Indonesian society, but has become a subject on the world stage. Since 2000, Indonesian Muslim Women who wear a headscarf found everywhere not limited socio-economic and cultural status. Muslim dress is no longer a Muslim identity, but has become a social identity in the community not only Indonesia and even the world. This means that halal lifestyle in Muslim dress is expected to increase as well as the growing demand. This is in line with Thomson Reuters Report (2015) that total clothing expenditure of Muslim population in the world reached 244 billion USD or 13.56 percent of the total Muslim consumer spending of 1.8 trillion USD, and is expected to grow along with the increasing economic Muslim countries. This phenomenon will open opportunities to compete on the world stage in the face of the global market. Indonesia as the largest muslim population in the world can be a business opportunity and market share positioned in this halal fashion industry. This study aims to examine how Muslim women understanding of the concept of halal lifestyle in fashion, to explore what efforts have been made by entrepreneurs in promoting their halal fashion business, and how the role of halal business fashion on women economic empowerment. This research is conducted in Yogyakarta province which is an example of cultural diversity as an educational and cultural center. The method of this research is mixed methods that involves collecting, analysing and integrating quantitative and qualitative research. From the results of interviews to the informants found that the motivation in running the business comes from yourself and influenced by the existing environment. Awareness of business opportunities along with increasing consumer demand has also existed. Some obstacles in running the business include the high price of raw materials and production costs and associated with capital assistance. The results of descriptive analysis and chi-square test show that fashion halal business / business play a role in empowering the economics of the respondents through employment opportunities, increased authority in making decisions (in their households), and in terms of income.