Background: Nursing students profession as a professional candidate in health care system is commonly faced the dilemma ethics during their clinical experiences. Consequently, they should have knowledge, readiness as well as competencies to solve the complexity problems related ethical issues in modern health care. Objectives: This studies was conducted to explore the perspectives and to describe level of knowledge of nursing student profession program about nurses ‘codes of ethics in academic hospital Universitas Muhammadiyah Yogyakarta, Indonesia. Methods: Mixed methods with quantitative and qualitative approaches were used. Data was collected from 83 nursing student’s profession for quantitative study and 11 students for qualitative study who had practiced at 3 teaching hospital of UMY. It was collected using questionnaires and in-depth interview during April-June 2016. The data analyzed using software statistic and content analysis. Findings: Seventy one point one percent (n=83) the knowledge level of nurses codes of ethics were good in questionnaire analyzed. The majority nurses and patient relationship was good (83,1%) and the minority of nurses and their organization was good (74,7%). Students qualitative responses have divided into two thematic categories including: definitions of ethics codes, contents of ethics (nurses and patients, nurses and practice, nurses and society, nurses and their colleagues, nurses and organization). The qualitative result was good for view of nursing student about definition and the content of nurse’s ethic codes. Conclusion: The perspectives of nurses ethic codes in nursing student profession is good in quantitative and qualitative analysis. Further research should focus on the implementation of ethic codes of nurses including assessment and evaluation methods.