A paradigm shift in curriculum has resulted in the implementation of students-centered learning (SCL) approach, putting students as the center of the learning process. This approach suggests different strategies from conventional learning which involves students’ active participation. This study aims at investigating teaching and learning strategies implemented in the classroom context to foster students-centeredness. This study also attempts to explore how the strategies are executed in the teaching and learning activities. Moreover, the significances and the challenges of implementing those strategies on the students-centeredness are identified at the last phase of the study. Six teachers, purposively selected, teaching at English Education Department of Universitas Muhammadiyah Yogyakarta became the participants of the study. Descriptive qualitative served as the research method employed in the current study. The data gathering instruments used were in-depth interview, classroom observation, and supporting documents. The interview data were transcribed, coded and categorized, then the observation checklist was constructed based on the interview result. Besides, each teachers’ syllabus was also analyzed as a secondary data to clarify and validate the research findings. The results of this study predict the implementation of various teaching strategies resulting on students-centered learning. The procedures, rules, and regulations of implementing the strategies in the teaching and learning activities are also highlighted. Furthermore, the findings also identify the significances and challenges of those learning strategies on students’ participation the learning process.