Children in endemic areas of Iodine de ciency disorders (IDD) are at risk for hypothyroidism that make disruption of growth and development. Children under 2 years olds is a critical age when there is a rapid growth in both physical and social development, mental, emotional, and intelligence that will greatly affect the growth of subsequent developments.The aim to determine the pro le of thyroid status and its relationship to growth and psychomotor development of children under the age of 2 years in an endemic area IDD.This research used analytic observational with cross sectional design. The subjects were 50 children under the age of 2 years in the village Ngargosari, Samigaluh, Kulonprogro. Measurement of levels of thyroid status (TSH and FT4) using ELISA method in the Laboratory of Research and Development of Iodine De ciency Disorders Borobudur Magelang. Physical growth indicators were measured include body weight, body length, body mass index (BMI) using indicators Z-score. Anthropometric measurements using a standardized measuring tool. Measurement of psychomotor development is done by using the Denver II test. Data were analyzed by Spearman correlation test.Retrieved median TSH level was 1,715 ng / dL (1.4 to 2.1 ng / dL) and the median levels of FT4 was 1,620 ng / dL (0.08 to 17.4 ng / dL).Thyroid status consist euthyroid82%,subclinical hypothyroidism14%, and subclinical hyperthyroidism 4%. Anthropometric results are generally within the normal range. But there are still 4% malnutrition, 6% thin, 2% very thin, and 4% fat. Four percent have short stature and 2% very short. Thyroid status with euthyroid distribution, Subclinical Hypothyroidism and Hyperthyroidism Subclinical, correlated with Weight to age (W/A) (p = 0.027; r = - 0.313). No signi cant correlation was found between thyroid status with Body Length / Age, Body Mass Index/Age, Body Weigth / Body Length. Psychomotor development of children consist advance 8% and normal 66%, but still found the subjects with suspected delays about 26%. Thyroid status is correlated to the development of  ne motor skills of children under two years of age (p = 0.027 and r = -0.320). Thyroid status did not correlate with the other three aspects, namely the development of gross motor, social and personal language.Thyroid status of children under 2 years olds consist euthyroid 82%, subclinical hypothyroidism14% and subclinical hyperthyroidism 4%. Thyroid status correlates to Weight/Age and  ne motor development.