Anatomy learning methods so far are still dominated by the method of learning using books. The material presented in the form of pictures and writings. Currently anatomy learning method using the book is done by redrawing parts and memorize the location and its terms. So, the student has difficulties when forgot and want to find the term on the anatomy, because it is not easy and takes a long time to look for it from the number of terms on the anatomical parts in the book. The purpose of this research is to create a system that can be used in studying anatomy especially dental anatomy through an android based application and can provide ease of anatomy of tooth learning using mayer principle of multimedia learning on application. Based on the results of system testing and user testing performed can be concluded that this application can be used as a medium of information and learning about tooth anatomy. This is evidenced by the results of black-box testing and the results of the questionnaire.