Strawberry (Fragaria x ananassa) consist of citric acid and weak malic acid that can affect salivary pH. The role of saliva pH is important in keeping oral health, because when it is too acid it can trigger dental caries, but when it is too alkaline it can form calculus. This research aimed at finding out whether strawberry extract can increase saliva pH and finding out the most effective treatment to increase saliva pH. The design of this research is clinical experimental using pretest and posttest design within subject to test the effectiveness of strawberry extract on salivary pH. There are 60 research subjects which are divided into 5 treatment groups consisting of Aquadest (negative control), 0.2% Chlorhexidine (positive control), 15% strawberry extract, 45% strawberry extract, and 75% strawberry extract. Each group has 12 subjects. The result of data analysis using hypothesis test of One Way Anova showed that p=0.001 (p<0.05), which means that there is a significant difference in every treatment and the Tukey test shows that 0.2% Chlorhexidine is the most effective treatment to increase saliva pH. This research shows that strawberry extract can affect saliva pH but to increase saliva pH, it is less effective than 0.2% Chlorhexidine.