This article discusses about M. Amin Abdullah’s thought (A professor at State Islamic University Sunan Kalijaga Yogyakarta) in the field of Islamic Studies. The method used in this paper is biographical-reflective method because the writer was his student. The focus of the writing is the heredity of the scientific methodology and its implication in the study of Islam in Indonesia. This article concludes several Islamic scientific heredities from M Amin Abdullah majoring on the integrative-interconnectivity concept in Islam that tends to be spaced out, especially in the study of Islamic classics. The other thought is about the importance of academic attitude in the development of the future Islamic study. In the scientific methodology aspect, he stresses the importance of the renewal in the Islamic contemporary study to spread the teachings on the earth as the sky heredity, sacral and transcendental, to dive the needs to answer various worldly problems that are empiric and immanent. The implication of Amin Abdullah’s thought gives new interpretation in the contemporary Islamic scientific study that is more contextualempirical and different from textual-normative classic Islamic study format.