Liver is the central metabolism and detoxification. Alcoholic hepatitis is a syndrome of inflammation of the liver, which generally occurs due to alcohol consumption progressively over a long period of time. Centela asiatica is a plant that believe to be hepatoprotector because there is antioxidant subtance . The purpose of this study was to examine the effectiveness of extract pegagan (Centela asiatica) in the rehabilitation of alcoholic liver in mice (Mus musculus) through observation of SGOT and SGPT. This study is pure experimental with pretest posttest control group design. Subject posttest control group research are mice (Mus musculus) androgynous male Swiss Webster age of 2-3 months with weight + 20 grams, totaling 30 subject were randomized into 6 groups, each group consisted of 5 mice. Alcoholic induction by red wine 14.7% as much as 1.12 mg / 20g BB orally 1 time a day for 21 days. Extract pegagan (Centela asiatica) was administered orally in accordance with the group. Sampling SGOT and SGPT done 3 times through orbital vein. The data was analyzed by one-way ANOVA followed Tuckey HSD test. Induction of 14,7% alcohol cause liver damage, evident from the significant increase is in the levels of SGOT and SGPT enzymes (p = 0,000). Induction of Centella asiatica leaf extract (Centella asiatica) has been shown to reduce levels of SGOT and SGPT enzymes (P = 0,000). SGPT value decrease of 13,10 IU/L and SGOT of 12,04 IU/L with Tuckey HSD test showed the effectiveness of Centella asiatica leaf extract (Centella asiatica) in improving liver function.