Background: Faculty of medicine is a faculty that has always been a favorite of designate students. Admission selection of medical faculty required a proper selection method in order to predict the academic achievement that will be produced. At Muhammadiyah University of Yogyakarta, the selection is divided into achievement lane, CBT, PBT Partnership and Regular PBT. In each lane will be done by a personality tests. This research is needed to see the correlation of university entry selection and students personality to academic achievement especially to know what dimension of personality that is influential. Method: This research is descriptive correlational with research design using cross sectional that done by 213 samples. The sample was obtained from students 2010, 2011 and 2012 classes that meet the criteria of inclusion and exclusion. Data obtained from the Education Server of FKIK UMY which is analyzed by using correlation test Chi-Square and Spearman. Result: There is a correlation between university entry selection to academic achievement with Asymp.Sig value of 0,043. Besides, the correlation between personality to academic achievement are GPA 60,9%, exam score 57,1%,and frequency remediation 45,5%. The dimensions that affect on GPA and exam score are conscientiousness while the dimension that affect the frequency of remediation is agreeableness. Conclusion: In this research, there is a correlation between university entry selection and personality toward academic achievement. The dimensions of personality that affect academic achievement are conscientiousness and agreeableness.