| dc.contributor.author | ORBAYINAH, SALMAH | |
| dc.contributor.author | PERMANA, KURNIA EKA | |
| dc.date.accessioned | 2016-09-15T07:03:42Z | |
| dc.date.available | 2016-09-15T07:03:42Z | |
| dc.date.issued | 2011-09 | |
| dc.identifier.uri | http://repository.umy.ac.id/handle/123456789/1983 | |
| dc.description | Buah anggur memiliki kandungan proanthosianidin dan
resveratrol yang berkaitan erat dengan
pencegahan hiperlipidemia khususnya hipertrigliserida. Penelitian ini bertujuan untuk mengetahui
pengaruh ekstrak buah anggur merah (
Vitis viniferra
L.) terhadap kadar trigliserida darah tikus putih
(
Rattus norvegicus).
Ekstrak anggur merah dibuat dalam berbagai dosis. Dosis I (100mg/200g BB/hari),
dosis II(250mg/200g BB/2ml), dan dosis III (500mg/200g BB/hari). Pemberian ekstrak anggur merah
dilakukan selama 10 hari. Hasil yang diperoleh menunjukkan bahwa terdapat perbedaan kadar trigliserida
yang signifikan sebelum dan sesudah perlakuan pada masing masing kelompok nilai (p<0,05). Pada uji
statistik menggunakan
one way
Anova menunjukkan nilai p=0,000 (p<0,05). Dosis Uji I mengalami
penurunan sebesar 32,80 ± 7,99 ml/dL, dosis Uji II yaitu 60,74 ± 2,15 ml/dL, Uji III yaitu 69,41±3,87ml/dL
sehingga terdapat perbedaan kadar trigliserida darah tikus putih antar kelompok yang signifikan.
Disimpulkan bahwa pemberian ekstrak anggur merah berpengaruh terhadap penurunan kadar trigliserida
darah tikus putih secara bermakna | en_US |
| dc.description.abstract | Grapes contain proanthosianidin and resveratrol are strongly associated with prevention of hyper-
lipidemia especially hypertriglyceride. This study aims to determine the influence of red grapes extracts
(Vitis viniferra L.) to the white rat blood triglyceride levels (Rattus norvegicus). Red grapes extracts is
made in various doses. I dose (100mg/200g BW / day), II dose (250mg/200g BW/2ml), and the third
dose (500mg/200g BW / day). Red grapes extract given during 10 days. The results show that there are
differences in triglyceride levels significant before and after treatment in each group values (p <0.05). On
the statistical test using one way ANOVA showed the value of p = 0.000 (p <0,05). I test dose decreased
by 32.80 ± 7.99 ml / dL, the dose Test II is 60.74 ± 2.15 ml / dL, Test III ie 69.41 ± 3.87 ml / dl so that there
are differences in blood triglyceride levels rats significantly between groups. It was concluded that red
grapes extract influence on decreased levels of blood triglycerides white rats significantly | en_US |
| dc.description.sponsorship | UMY | en_US |
| dc.language.iso | other | en_US |
| dc.publisher | Mutiara Medika UMY | en_US |
| dc.relation.ispartofseries | Vol. 11 No. 3: 175-180,; | |
| dc.source | Mutiara Medika Vol. 11 No. 3: 175-180, September 2011 | |
| dc.subject | grapes extracts, triglyceride, Rattus norvegicus | en_US |
| dc.title | THE INFLUENCE OF RED GRAPES EXTRACT (VITIS VINIFERA L) TO THE BLOOD TRIGLYCERIDE LEVELS WHITE RATS (RATTUS NOVERGICUSS) | en_US |
| dc.type | Article | en_US |
