Background: Stroke is a clinical manifestation of both focal and global cerebral dysfunctional disorders, lasting more than 24 hours or ending with death, without the discovery of causes other than brain vascular disorders. One of the risk factors for stroke is the stiffness of blood vessels that can be detected by pulse pressure measurement. Pulse pressure is the difference between systolic and diastolic blood pressure. The purpose of this study was to determine the relationship between pulse rate and stroke prevalence. Methods: This study was an observational study with cross-sectional design, conducted on 198 patients who had been hospitalized in RSUD Agoesdjam Ketapang, from May 2015-2016 with age range 50-75 years, the data retrieved by consecutive sampling. Patient data obtained from medical record. Results: Chi-Square analysis result of each age group yield p value <0,05. The results of the correlation test in patients age group 50-55, 56-60 and 61-65 years showed moderate correlation strength, in group 66-70 and 71-75 years showed strong correlation strength. Conclusions: High pulse pressure is associated with stroke prevalence. Increasing the age of a person increases the risk of stroke because of the higher pulse pressure.