Background: The rapid development of hospitals has resulted in intense competition, which demands competition for patient products and trust. PKU Muhammadiyah Yogyakarta and Gamping Hospital are private hospitals that collaborate with BPJS as referral hospitals in the Special Region of Yogyakarta and Central Java. In its mission, every hospital is required to provide optimal and satisfying health services for all levels of society and accompanied by Islamic elements in the health sector. Hospitals that fail to satisfy their customers will face more complicated problems due to negative word-of-mouth impacts. Subject and Method: This research is an analytical study with cross sectional design. The population of this study were class III JKN patients in hemodialysis units at PKU Muhammadiyah Yogyakarta and Gamping Hospital in 1 untill 20 February 2018 as many as 264 people. The sample of this study is 160 people with sampling techniques based on Krecjie & Morgan formula. Data analysis using the t-test method. Result: The satisfaction of JKN Patients in the Hemodialysis Unit at PKU Muhammadiyah Yogyakarta Hospital in Yogyakarta as many as 55 (68.8%) respondents expressed satisfaction; while the PKU Muhammadiyah Gamping Hospital as many as 72 (90.0%) respondents said they were very satisfied; Patient’s Satisfaction Differences in PKU Muhammadiyah Yogyakarta and Gamping Hospital has been determined from 5 aspects, there are 2 aspects of having different satisfaction, such as tangibles and responsiveness. PKU Muhammadiyah Gamping Hospital is known to be more satisfying than PKU Yogyakarta both from tangibles and responsiveness. Other aspects such as reliability, assurance, and empathy between the two hospitals are known to have no difference. Conclusion: Among all of the 5 aspects of satisfaction, there are 2 aspect that have satisfaction differences between PKU Muhammdiyah Yogyakarta xi Hospital and PKU Muhammadiyah Gamping Hospital, such as tangibles and responsiveness. Keywords: Patient’s Satisfaction, JKN