Background: Queen Latifa General Hospital is type D hospital that will be developed to be type C hospital. It needs to do the research about how the level of patient satisfaction towards the service of Queen Latifa General Hospital so that it is able to know about quality of hospital service in order to be type C hospital in the future. Method: This research uses non-experimental quantitative design, with descriptive regression design, Results and Discussion: The results of Multiple Regression Analysis Value of 0.29 on tangibles variable is positive, the value of -0.24 in Reliability variable is negative, the value of -0.21 on responsiveness variable is negative, the value of 0.64 on assurance variable is positive, and the value of 0.35 on the empathy variable is positive, so that it can be concluded that the higher the quality of empathy, the higher the patient satisfaction will be. Conclusion: The service quality at Queen Latifa General Hospital has been running well in terms of quality of tangibles, reliability, responsiveness, assurance, and empathy. Keywords: Service Quality, Patient Satisfaction