This study aims to identify the potential vulnerability on the railway track a result of natural disasters. The research takes the focus on the identification of multi-hazard disaster on the railway track Yogyakarta-Cilacap. The analysis of multi-hazard disaster produces multi-hazard mapping using ArcGIS software. Assessment of multi-hazard disaster is based on scoring and weighting event of the observed variables influence is natural disasters. Multi-hazard disaster consists of three (3) level vulnerability, low level of vulnerability, medium level of vulnerability and high level of vulnerability. The potential multi-hazard disaster is retrieved from a data source such as the landform, map of disaster prone areas, rivers data, contour data, and geological data. The results show that there was some threat of natural disasters that potentially occur on the railway track Yogyakarta-Cilacap i.e. flood, earthquakes, volcanoes and land subsidence. Based on the mapping of multi-hazard disaster, railway track Yogyakarta-Cilacap has 26% of high level of vulnerability, 15% of medium level of vulnerability 15% and 59% of low level of vulnerability from all observed railway track of Yogyakarta to Cilacap