Measuring the result of study is a component of nursing education. One of measurement methods for the study result of nursing student is Multiple Choices Question (MCQ). MCQ with good quality should have a question difficulty that is appropriate with the student level of understanding so that the average MCQ result of student should not be too low due to difficult MCQ questions nor too high due to easy MCQ questions. The quality of MCQ difficulty can be studied by anaylizing and evaluating every questions item. Research Objective: This research has the purpose of understanding if there is any connection between MCQ question difficulty againts the result of MCQ of PSIK FKIK UMY nursing student of class of 2014. Research Method: The research design is quantitative decsriptive with cross sectional approach. The samples in this research are 10 documents of question item analysis and the result of MCQ test of nursing student of class of 2014. The sampling technique of this research is purposive sampling. The instrument of this research is item analysis which consisted of item difficulty, item discrimination and distractor effectivity. Data analysis in this study used Microsoft Excel and Kendal Tau analysis. Result: Analytic result show significant value of p-value as many as 0,001 (P<0,05), which means thre is a significant relationship between the level of difficulty of Multiple Choice Question (MCQ) problem with the 2014 student learning outcomes of the PSIK FKIK UMY. Conclusion: There is a significant connection between MCQ question difficulty and the study result of nursing student of class of 2014 of PSIK FKIK UMY.