Background: Medical education institutions have an obligation to develop the readiness of their students to study independently. The development of the readiness of student self-studying requires an assessment of the readiness that students have for independent learning. Self directed learning is an independent learning process whereby learners can determine their own learning needs independently. Individuals are able to determine learning needs, learning objectives, learning resources, learning strategies and assessing learning outcomes. This research aims to find out the influence of self-directed learning method towards the learning outcomes of Medical Faculty student in UMY. Method: The type of researchin this study was non experimental with analytic observational research design using cross sectional approach, with stratified random sampling technique with a total sample of 229 students. The instrument used is self-Rating Scale for Self-Directedness in Learning (SRSSDL) by Fisher Instruments. Test analysis using simple linear regression test. Result: The results of this study show that there is no effect of SDL on the value of PSK student learning outcomes (p=0,22) for the batch of 2014 , (p=0,61) for the batch of 2015, (p=0,16) for the batch 0f 2016. It shows that there is no effect of SDL towards learning outcomes score in medical students of UMY. Conclusion: There is no impact of SDL (Self Directed Learning) towards learning outcomes score in medical student of UMY.