Purpose of the study: This study aims to examine the effect of Nasyiatul Aisyiyah business on the development of its member’s self-potential, a case study in Central Java. There are several research findings that reinforce the involvement of members of the BUANA community in the activities of small and enterprises both on government agencies and private. Methodology: This research used to survey, the data source of this research is primary data, collected using questionnaire instrument, Data measurement using interval scale, with a five-point Likert scale score. This research conducts analysis to 100 participants in Nasyiatul Aisyiyah member in Kendal Central Java as sample. Results: The finding of research indicates that BUANA has become a model for the entrepreneurial organization. Obviously, BUANA is a form of business practices as its members would have a lot of experiences and skills to become an independent and creative business woman. BUANA has become a superior program as it managed to enhance the spirit of entrepreneurship among its members. BUANA is also the real laboratory for Nasyiatul Aisyiyah Organization. Every region in Indonesia obliged to own BUANA. The limitation of this research: This research only focuses on Central Java. Future improvement may involve other regions outside Java. Applications of this study: This research is suitable in explaining the phenomena of women entrepreneurship in Central Java and how they contribute to the local economy. More programs and activities can be organized to ensure that BUANA may become more productive and innovative in the near future to further boost Nasyiatul Aisyiyah’s economy. Novelty/Originality of this study: The novelty of this research that BUANA is a tangible manifestation of organizational entrepreneurship from branch-region to center.