The purpose of this study is to analyze the factors that affect profitability in foreign banks in Indonesia after the monetary crisis in 1998. The data used in this study is secondary data per month which is obtained through Bank Indonesia and the Financial Services Authority with This research period was January 2002 - December 2004. The independent variables or independent variables used in this study were Non Performing Loans (NPL), Operational Costs divided by Operating Income (BOPO), Capital Adequacy Ratio (CAR), while the dependent variable or bound to use Return On Assets (ROA) as a measure of the level of profitability of foreign banks in Indonesia. Data analysis using multiple linear regression analysis with program Eviews 9. Based on the results of this study the results obtained that Non Performing Loans (NPL) and Operational Costs divided by Operating Income (BOPO) have a negative and significant effect on Asset Ratio (ROA) while Capital Adequacy Ratio (CAR) has a positive and significant influence on Asset Ratio (ROA) with a probability value smaller than 0.05, simultaneously NPL BOPO, CAR has a significant effect on ROA. Adjusted R square value (coefficient of determination) is 0.744825 or 74.48% Ratio On Assets (ROA) can be explained by NPL, CAR, and BOPO while the remaining 25.52% is explained by other variables outside of this research.