This research aims to find out what are the factors that affecting the source of shock on Islamic banking at post 2008 global financial crisis in Indonesia. Types of data in this research using secondary data obtained from the Central Bureau of statistics, Bank Indonesia website, investing, and the financial services authority. The methods in this study using Multiple Linear regression analysis with the Ordinary Least Square (OLS). To find out the factors that influence the sources of shock on Islamic banking that is using shock with proxy a variable of Non Performing Financing (NPF) as the dependent variable, while the inflation, depreciation of exchange rates, Gross Domestic Product ( The GDP), and oil prices as the independent variable. The sample data in this research using of data (time series) quarterly in 2009 first quarter until 2018 of third quarter. Based on the results of the research show that the negative effect of variable inflation and not significantly of Non Performing Financing (NPF). While the variable exchange rates, Gross Domestic Product (GDP), and oil prices influential significantly. For the variable influential positive of the exchange rate while the veriabel Gross Domestic Product (GDP) and oil prices are influential negative. The coefficient of determination of the regression models showed that a change in variable Non Performing Financing (NPF) 63% caused by the four variables are examined, while the rest 37% is affected by other factors that are not incorporated into the model of research.