Abstract Congestive Heart Failure, or CHF for short, is a progressive clinical syndrome caused by inability of the heart to pump sufficient blood to meet the body’s metabolic needs. The treatment of CHF varies widely from patient to patient in order to cause the incidence of drug related problems (DRPs). Therefore, the necessary of DRPs identification to achieve patient’s therapy outcome. The main aim of this research study was to determine the description of cardiovascular pharmacotherapy in patients with congestive heart failure as well as to determine the incidence of Drug Related Problems and to analyze the Drug Related Problems (DRPs). This research was conducted by a non-experimental descriptive study with retrospective data collection of 20 medical recordwith CHF during January to May 2015, then the DRPs were analyzed using literature analysis, such as hospital standards of medical services, Pharmacotherapy Handbook 9th edition 2015, New York Heart Association (NYHA), Drug Interaction Facts (DIF), and (Persatuan Kardiologis Indonesia (PERKI). Based on this research study, there were 20 patients who had 42 DRPs. The DRPs consist of one adverse drug reaction (2.38%), 26 drug choice problems (61.90%), one drug use problems (2.38%), 14 drug interactions (33.33%), and no dosing problems were found. Keywords: Congestive Heart Failure (CHF), Drug Related Problems (DRP), Panembahan Senopati Public Hospital, Inpatients, Cardiovascular pharmacotherapy.