Wounds are classified as acu te and chronic. The early stage of chronic wound formation are cha racterized by the emergence of g ram - positive and gram - negative organisms . such as Staphylococcus Aureus and Escherichia coli. At a later stage, Gram - negative Pseudomonas species tend to attack the inner layers of the wound. Modern wound dressings containing antimicrobials that have been develo ped since the last twenty years. It is e ffec tively to kill b acteria and fungi in the wounds and to prevent recurrent infections during wound healings. The purpose of this paper is to report the results of a review that focuses on the effect of modern wound dressing on Staphylococcus Aureus bacteria . Relevant articles were searched in PubMed and google’s scholar using keywords "modern wound dressing", "antibacterial", "staphylococcus". Ten a rticles that fit with the inclusion criteria wer e included in this review . The results show Modern wound dressi ng with antimicrobial content can inhibit bacterial growth. Interm of time and type of bactreria. Thus, this literatures review can be the basis for further researchs on the effectiveness of modern wound dressing s against Staphylococcus Aureus .