Dengue haemorrhagic fever (DHF) is a disease transmitted by Aedes mosquito still a health problem in the tropics area, including Indonesia. Incidence of dengue is closely related to the presence of the mosquito vector. Aedes aegypti as the primary vector were live not far from human life activities, has a breeding place in the form of stagnant clear water in and around the house. Vectorial capacity affected by the survival of vector and extrinsic incubation of the virus. The survival of mosquito was influenced by humidity that is maintained by the presence of vegetation. This study aims to prove the correlation of land cover against dengue. Land cover is in the form of a percentage of the building area on vegetation surrounding the patient location with 200m diameter was determined by the geographic information system (GIS) approaches and remote sensing. Results showed that 44.44% of dengue cases occurred in the environment by building 31-60%; 44.83% of cases in 61-90% of the buildings, only 6.89% in <30% of the buildings and 3.83% at more than 90% of the building. Spearman correlation test was proved that there is a correlation between the land cover and DHF (p = 0.000; r = -0.815). This suggests that the greater the percentage of the building, the lower the dengue cases in Sleman, Yogyakarta, Indonesia.