A research "Effect of Rabbit Manure and N, P and K Fertilizers from Stool Balance on Growth and Yield of Purple Eggplant (Solanum melongena L) on Regosol" was completed in the Experimental Field of the Faculty of Agriculture, Muhammadiyah University, Yogyakarta in April 2019 to July 2019. This study aims to determine the effect of rabbit manure and N, P and K fertilizer on eggplant growth in regosol soil. The design used is a Completely Randomized Design (CRD) consisting of 5 treatments, namely: 100% inorganic N, P, and K fertilizers; 25% Manure + 75% inorganic N, P and K fertilizer; 50% Manure + 50% inorganic N, P and K fertilizer; 75% Rabbit Fertilizer + 25% inorganic N, P and K fertilizer; 100% Manure. The observations were analyzed using variance or Analysis of Variance with α: 5% level. If there is a real difference in effect between the treatments tested, further tests are performed using Duncan's Multiple Range Test with α: 5% level. The results showed that all counter treatment gave the same effect on the growth and yield of purple eggplant, namely plant height, number of leaves, number of fruits, total fruit weight and diameter. 100% treatment of Manure is the best treatment in the growth and yield of purple eggplant plants that are plant height, number of leaves, leaf area, plant fresh weight, plant dry weight, root length and fruit length