Background: Diabetes has become on of main threats to human health in the 21 st century. Management of type 2 diabetes is expected to prevent and reduce acute and chronic complications, especially by apliying self care behavior. DSME can facilitate patients in term of knowledge, skills and abilities to prevent further complications. Purpose: This study aims to determine the effectiveness of DSME on self care behavior of people with type 2 DM. Method: The study design was conducted using quasi – experimental with pretes- posttest desaign. Respondents in this study were sufferers of type 2 DM from the result of PISS-PK assessment in the work area of ngawen community helath center with 54 respondents. Analysis of the data from the result of the study used paired t-test and independent t-test to determine the effectiveness of DSME. Result : There is a significant difference in the self care behavior (value ρ 0,02) where this value < α, in the intervention group and control group. Conclusion: This study show that Diabetes Self Managemeent Education is effective against selfcare in people with type 2 diabetes.