Diabetes self-empowerment is one of important aspect to control diabeetes. The empowerment patients are able to self-manage theeir diabetes and achieve better glucose control. There are several factors that influence patients empowerment including individual factors, perceived benefits, perceived barriers, knowledge, family support, self efficacy, and economy. The objective of this study was to assess the empowerment needs of diabetes self-management among patients woth type 2 DM in PKU Muhammadiyah Yogyakarta. This was description study with cross sectional approach. Thirty five respondents which were selected through accidental sampling participated in this study. The data were colloected by using the SDSCA, the DES-SF, and empowerment needs questionnairs. The empowerment needs consisted of knowledge, perceived benefits, perceived barriers, and self-efficacy. The data were analyzed by using description statistics. The result of the study showed that 18 respondents (51.4%) had high self-management behavior and 31 respondents (88.6%) had positive attitudes towards self –empowerment. The patients perceived benefits, knowledge and self-efficacy were in moderate level (91.4%, 71.4%, and 77.1%) respectively. The patients perceived barriers were low (51.4%). To be an empowerment patients. They must improve their perceived benefits, knowledge, and self-efficacy. Nurse must consider the aspects that need to be improved to promote better diabetes self-management. Further research is needed to determine various factorss thaat can empower the patients.