Palliative care is a treatment that is carried out to improve the quality of life of patients and families in the face of patients who have life-threatening diseases both physical, psychosocial, and spiritual. There are 40 million people in the world each year who need palliative care, especially in non-communicable diseases. Most families of patients who care for palliative patients at home feel burdened both physically and psychologically. This is because the daily activities that must be done are limited because all activities are focused on being a caregiver. This makes it important for the family cadres who have the knowledge and skills to provide primary care to palliative patients at home. The establishment of the family cadres as the main nurse for palliative patients at home is one manifestation of community empowerment and is the right step in optimizing government health programs in improving the quality of life for palliative patients. The method of activity is based on the health promotion model, where activities are focused on efforts to improve the ability of the community through community learning. The formation of the family cadres was initiated by a socialization activity and then the cadres were given health education in the form of counseling and skills training. The result of the activity was that all cadres (100%) were able to handle the symptoms of palliative patients at home and could re-practice palliative care at home after attending the training. The follow-up plan of activities is an effort to maintain cadre performance. The need to collaborate with hospitals or Puskesmas (the Indonesian community health service center) which will send palliative patients back after hospitalization so that the quality of caregivers can be continued by family cadres and health cadres. The implementation of the activity received appreciation from the government officials present