Cardiovascular disease has been responsible for 37% of the total death in Indonesia. Research about cardiovascular disease and its management in Indonesia has heavily emphasised biomedical aspects of the disease; little is known about experiencing the disease at the individual’s level, especially for those Indonesian women with cardiovascular disease. The aim of this study was to understand how gender shapes Indonesian women’s experiences of living with heart disease and how it affects their private lives. A feminist-informed qualitative research design was carried out in the study. The primary method of data collection was semistructured interviews. A total of 26 women aged between 30 and 67 years were interviewed from June to September 2016. Transcribed interviews data were analysed using qualitative framework analysis. Three major themes were inferred from the data analysis: (1) effect of CVD on women’s day-to-day activities, (2) effects on women’s family relationship, and (3) women’s coping strategies. The inability to fulfil the gender expectation of caring for others had unwittingly managed to undermine or threaten the women’s sense of self and their social identity. Healthcare professionals should be aware of the ethnic and cultural backgrounds of women with cardiovascular disease, to enable them to deliver services that meet the social, spiritual, and cultural needs of their patients.