Knowledge is dynamic and growing in the social interaction between individuals and organizations. Sharing knowledge is important for the organization in realizing innovation. In sharing knowledge there are cultural factors that differ among members of the organization. Organizational culture according to Schein (2010) is an abstraction which created the power of social situations and organizations from a strong culture. This article is a conceptual framework that describes the organizational culture with the four dimensions, namely trust, communication, leadership and reward. The dimensions will be reviewed and analyzed its correlation with knowledge sharing and how to promote the establishment of organizational innovation. The purpose of this article is a conceptual framework correlation organizational culture and unified knowledge sharing: 1) How is the cultural and organizational support can encourage the implementation of an integrated knowledge sharing, 2) How integrated knowledge sharing can contribute to the realization of organizational innovation. Novelty proposed in this article is unified knowledge sharing, as a mediating variable between culture and organizational innovation.