Surgical Site Infection (SSI) constitutes one type of health care or Healthcare Associated Infection (HAIs) that indicator hospital quality. Surgical Site Infection (SSI) can cause the incidence of health care. In implementation bundles can reduce 4.9% incidence of clean operations and 19.4 4% of contaminated operations. The SSI incident before the application is larger than that reported in previous research (4.9% vs 3.7%). (fernandez-prada et al. 2017). Research aims to determine the implementation of bundles care for SSI prevention in the preoperative stages of RSUD "X" in Kebumen, descriptions of manager and functional staff support of Standard Operating Procedures(SOP) bundles preoperational prevention SSI. Methode research mix method with a design retrospective crosssectional. The subject of quantitative research is a patient who performed general surgery with untreated clean and contaminated wounds. Qualitative research subjects are hospital managers and functional staff related to the application of SOP bundles prevention of SSI. Quantitative data collection is done by studying medical records using pain tools through SOP Bundles Care for SSI prevention. Data collection is done with interviews. Research : The highest implementation of the third bundle of the third, normolicemic / normotemperatureb 99.64%, is at a minimum of the lowest indexing of second bundle indexing area surgical clipper implementation 0.00%. Compliance with SOP Bundles Care for the Prevention of Surgical Site Infection in RSUD "X" in Kebumen with less than 55,54% of category. Hospital managers, functional medical and nursing staff 100% support the application of SOP bundles of prevention Surgical Site Infection with socialized follow-up plans, assessments and assistive facilities.