Hospital pharmaceutical installation services play an important role in efforts to improve the quality of hospital services. The quality of hospital services affects outpatient satisfaction. A level of satisfaction is the difference between perceived performance and expectations.The satisfaction of patient can affect the quality of the hospital.This study aims to determine the effect of pharmaceutical service quality on outpatient satisfaction in Tipe D Hospital Yogyakarta. This type of research is quantitative. The participated sample is outpatients who meet the inclusion criteria in Tipe D Hospital. Retrieval of data use a questionnaire with purposive sampling. Multivariate data analysis use multiple regression analysis. The results showed that the dimensions of pharmaceutical service quality that influence outpatient satisfaction are tangible. Dimensions of pharmaceutical service quality that do not affect outpatient satisfaction are reliability, responsiveness, assurance and empathy. The overall dimentions of pharmaceutical service quality (reliability, responsiveness, certainty, empathy and tangible ) affect satisfaction of outpatient in Tipe D Hospital Yogyakarta (t 7.239; p 0.000)