Hypertension is a health problem for the majority of people in Indonesia. The Efforts to reduce the incidence rate of hypertension and improve the quality of life are by changing the healthy lifestyle and by being in taking. To realize healthy lifestyle and behavior of hypertension, self-efficacy and support of the family as well as health care cooperation with the parties, the family, and society are required. The purpose of this research is to know if self-efficacy and family support improve the quality of life of patients with hypertension. This research is a pre-experimental research with OneGroup Pre-Post test design approach. The study was conducted in 50 people with the stratified random sampling technique in Ketawang Village, Gondang District, for 8 weeks. Measurement instrument of the quality of life was the WHOQOLBREF questionnaire was given before and after the patients were given self-efficacy and family support. The data was analyzed using SPSS 21 with Wilcoxon test. The Statistical test results obtained p value 0.000 so that there is a meaningful value that self-efficacy counseling and family support improve the quality of life of patients with hypertension with an average change of 4.46. Self-efficacy counseling and family support improve the quality of life for patients with hypertension, so they needs to be developed to reduce hypertension complications