In Indonesia, as in many other countries, unemployment is one of the most important problems need to solve. Among unemployed workforce, “unemployed intellectuals” need more concern than the lower educated unemployment, both psychologically and politically. One of the idea to settle the problem is reinventing entrepreneurship in Indonesia’s higher education system. It is hopeful that a new generation of intellectual and higher educated-based entrepreneur would be born and in this globalized economy, they could take part to support Indonesia’s trade diplomacy. This paper is addressed to some important elements, especially the policy makers, and at minimum to open the eyes of young generation to think about being entrepreneurs, not just for domestic trade and market, but also could play a significant role in the world economy along with Indonesia’s progressive trade diplomacy.