Background: Schizophrenia is a syndrome with a variety of causes and course of the disease is widespread, as well as some of the consequences that depend on the balance of influence of genetic, physical and cultural. Schizophrenia is a psychotic disorder that is chronic, often subside, but the signage is missing with clinical manifestations very wide variation adjustment pramorbid, symptoms and course of the disease vary widely There is still a lack of studies that discuss related to the relationship of cognitive function with social functioning of patients with schizophrenia, this study needs performed to evaluate the relationship between cognitive function with social functioning of patients with schizophrenia. Methods: Used the design of Spearman’s correlation. Sampling with consecutive sampling technique. The instrument used is the Personal Data Questionnaire,Morinsky Medication Adherence Scale (MMAS), Personaland Social Performance Scale (PSP). Analysis of the data used is cross sectional. Results: In the group of patients with schizophrenia the study subjects were males 63 (63,6%) and females 36 (36,3%). Age subjects mostly aged between 20- 40 years were 61 (61.6%). Most of the research subjects did not work as much as 74 (74.7%). Marital status of research subjects are mostly married by 60 (60.6%). Long illness most of the research subject is> 10 years (52.5%). While family history on the subject of the greatest sample is no (70.7%). The results of Spearman’s correlation analysis found medication adherence variables with p values of social function is 0.961, which means that the value of p>0.05. Conclusion: There is no relationship between medication adherence with social functioning of patients with schizophrenia.