Russia's relations with Iran has existed for a long time. In 1990 the Soviet Union began a dialogue with Iran on the possible completion of the process of building the Bushehr reactor and resumed in January 1995, where the Russian Federation officially declared will help Iran complete the Bushehr reactor building process. United States began to show strong opposition to the existence of the Bushehr reactor is feared to be used by Iran as the proliferation of weapons of mass destruction facilities. This research aims to make Russia's nuclear cooperation policy towards Iran. The method used was descriptive method by using secondary data. While the techniques of data collection through library research. Theories and concepts used are international political theory, balance of power and the concept of national interest. Russia's national interests in the cooperation on Iran seen from economic interests and military security that is aimed at restoring the country from economic crisis. in this case Iran to continue cooperation in the sectors of trade and exchange. Both countries are mutually use each other's position related to the Iranian nuclear issue