Autism was nuisance in communication development, social interaction, can’t observe and process information. In Daerah Istimewa Yogyakarta, nowadays, there were 272 autism children and number of male autism children bigger than female. This research aim’s was to find out influence of Murottal therapy toward communication ability of autism children at SLBN 1 Bantul Yogyakarta. The design of research used pre-experimental, pre-test and post-test without control group. The research was implement in June 2016. The amount sample of this research was 12 students who chosen with total sampling technique grounded on inclusion and exclusion criteria. Communication ability of respondents measured with Autism Treatment Evaluation Checklist (ATEC). This research used Paired T-test data analysis with value of p= <0,005. The result of research indicated that average of communication ability before and after murottal therapy i.e., pre-test 9, 25 and post-test 10.00 with value p=0,69 (p>0,005). Communication ability of autism children at SLBN 1 Bantul before and after intervention improved but not significant. There was no influence murottal therapy toward communication ability of autism children at SLBN 1 Bantul.