This study aims to examine the influence of interest and, profit sharing rates, inflasion, and size of organizations to mudharabah deposits at Bank Pembiayaan Rakyat Syariah (BPRS). This study uses secondary data quarterly financial report that BPRS in December 2014 until December 2015 periode that published by the Bank Indonesia. From the analysis carried out by preparing the obtained result that are collectively the same independent variables (Interest rates, profit sharing, inflation, and size of organizations) was able to influence the dependent variable that is mudharabah deposits. The methodology used is a linier regression model. The results showed : (1) Interest rates is a significant negative effect on mudharabah deposits. (2)Pprofit sharing is a significant positive effect on mudharabah deposits. (3) Inflation is a significant negative effect on mudharabah deposits. (4) Size of organizations is a significant positive effect on mudharabah deposits.