This study aimed to know the correlation of Muhammadiyah cadres religiosity toward their preference to become customers of Islamic {syari’ah} Banks. The subjects of this study was Muhammadiyah cadres at Kauman Yogyakarta by taking the sample from each ortom there. This study was quantitatif research method by using primary data. The sample used in this study was 55 respondents which selected using proportionate stratified random sampling. The data was analyzed using double linear regression and the calculation of the data was run using SPSS 15.0. Based on the result of the study that had been conducted into two independent variables namely dimensions of religious practice and dimensions of religious knowledge has a significant influence on the preference of Muhammadiyah cadres at Kauman Yogyakarta to become a customer of Islamic {syari’ah} Bank. While the dimensions of beliefs, experiences, and the consequences did not affect the preferences of Muhammadiyah cadres at Kauman Yogyakarta to become a customer of Islamic {syari’ah} Bank.