Background: Oral health is often ignored by most of people. They do not understand that the oral cavity is the entry access of germ and bacteria that could cause disease. Tooth cavities are still commonly found in children. Children in primary school age are vulnerable to oral disease because children tend to have behavior or habits those are less supportive for good oral health. Purpose: To know the influence of oral health education with Power Point media towards level of oral health knowledge in 7-8 years old students in SDN Minomartani 1 Yogyakarta. Method: This research used experimental research type with one group pretest-posttest research design. This research was held in SDN Minomartani 1 Yogyakarta in June 2016. Result: Based on Paired-t test to 24 sample, the significant value was 0.014 (p <0.05), which means that there was influence of oral health education by using Power Point media towards level of oral health knowledge in 7-8 years old students. Conclusion: There is influence of oral health education with Power Point media towards level of oral health knowledge of 7-8 years old students in SDN Minomartani 1 Yogyakarta.