the aims of the research is to analyze the production expense, income, income, profit and feasibility of catfish breeding business in Mino Ngremboko Sleman. The method used in this research is descriptive of respondents with census method as much as 60 people. Technique data gathering which is the researcher used is interview after the interview the researcher distributes the Questionnaire and doing an observation to fish hatchery business in Mino Ngremboko. The total expense suffered by fish farmers is Rp 1.503.813 consisting of explicit costs and implicit expense. Received revenue is Rp 5.061.275. The profit earned is Rp. 3.557.461, the productivity of investment is Rp 3.557.461. The productivity of the area in their place is 415%, labor productivity in getting for Rp 116.875/m2 and the feasibility of catfish planting business in Mino Ngremboko obtained a value of 3,41 means R / C> 1 then the determination seeding of catfish can be said feasible.