Adherence and colonization of Candida species particularly C. albicans on denture surfaces, forms a microbial biofilm, which may result denture stomatitis that mostly found in complete denture users. Purpose : The purpose of the present study was to evaluate the effectiveness of Salacca zalacca extracts in inhibiting the growth of Candida albicans on experimentally contaminated resin acryl plates. Materials and Methods : In the present experimental study, 32 resin acrylic plates (10 × 10 × 1 mm) were contaminated by immersion in 108 CFU/ml C. albicans suspension for 24 hours. The 32 plates were divided into two groups of 16 and immersed for 8 hours in Salacca zalacca extract 100% of concentration as test and sterile aquades as the negative control. The serial dilution was done and planted into the saboroud agar media then incubated for 48 hours. The remaining Candida albicans colonization on each growth media was enumerated and data were analyzed using the SPSS 16 software with Independent T-tests. Results : The result showed that the average number of the Candida albicans in the tested group was 0,00225 and the average number of Candida albicans in the control group was 0,0072. The result of the data analyses with Independent Sample T-test showed the value of p = 0,000 (p<0,05) which means there were significant differences in the growth of Candida albicans between tested group and control group. Conclusion : The extract of Salacca zalacca showed effective in inhibiting the growth of Candida albicans on the resin acryl plate.