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03. DISSERTATIONS AND THESIS
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Undergraduate Thesis
Faculty of Medicine and Health Science
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UMY Repository
03. DISSERTATIONS AND THESIS
Students
Undergraduate Thesis
Faculty of Medicine and Health Science
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brain injury, tracheostomy, glasgow coma scale, mechanical ventilator. cedera otak, trakeostomi, glasgow coma scale, ventilator mekanik (1)
braket Roth (1)
Breast Cancer, HER-2, Histological Grade. Kanker Payudara, HER-2, Grade Histologi (1)
Breast cancer, HER-2/neu, tumor size. Background: In 2012, worldwide there were 1.7 million new cases of breast cancer. Knowledge of HER-2 and tumor size can be used as the best indicator of prognostic factors and treatment of breast cancer. The function of the HER-2 strongly associated in the setting of tumor size growth. When there is overexpression of HER-2 will lead to growth in the size of the tumor had become unmanageable. This study was conducted to determine the comparation between HER-2 with the size of tumors in breast cancer patients. Aim: To determine the comparation between overexpression of HER-2 with tumor size in patients with breast cancer. Methods: Cross sectional study was carried out against 72 Patients with a diagnosis of breast cancer that has been conducted immunohistochemical examination (oncoprotein HER-2/neu) and histopathological (tumor size). Sampling research from January to December 2015. Data were analyzed by Chi- Square test done gradually include univariate and bivariate analysis. Results: From 72 samples obtained from the study of patients with tumor size ≤5 cm and> 5cm by 47 (65.3%) and 25 (34.7%) patients. In size ≤2 cm and> 2 cm by 24 (33.3%) and 48 (66.7%) patients, while the expression HER-2 positive in 26 (36.1%) patients and HER-2 negative with 46 (63.9%). By using the Chi-square test of correlation values obtained P = 0.119 for the size tumor ≤5 cm and> 5cm and P = 0.489 for tumor size ≤2 cm and> 2 cm for the comparation between the size of the tumor with overexpression of HER-2. Conclusion: No comparation was statistically significant overexpression of HER- 2 with large tumor size in patients with breast cancer. (1)
Breast cancer, Peripheral Blood Leukocytes, Karnofsky Score. Kanker Payudara, Leukosit Darah Perifer, Skor Karnofsky. (1)
BRONKUS (1)
BUAH ANGGUR (1)
BUAH CIPLUKAN (1)
BUAH DELIMA (1)
buah nanas (Ananas comosus) (1)
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