Background : Indonesia is one of the largest cigarette consuming fifth in the world. The prevalence of smokers in Indonesia as much as 34.7% and most of them are middle-aged teens to adults. Smoking is a current trend in society as a search for identity. Smoking behavior also have a negative impact to the users. Research purposes : To determine the relationships self-esteem with tobacco smoking behavior students S1 PSIK in FKIK UMY Research methods : This type of research is non-experimental research design with cross sectional correlative approach. Respondents in this study is as much as 30 respondents. Data were analyzed using analysis of correlation variable level or rank order correlation of Spearman difference. Research result :Respondents with smoking behavior, most are at the age of 22 years, amounting to 9 people (30.0%), Class of 2014 amounted to 12 (40.0%), early to know cigarette at the age of 12 years, amounting to 10 (33.3%), consumption of cigarettes in a day spent at most 12 rods and 13 rods, amounting respectively 5 people (16.7%), and the initial effects know-largest cigarette from friends totaling 20 people (66.7%) with the overall results of the students have the smoking behavior was very bad and self-esteem negative as many as 27 people. conclusion:Overview majority of smoking behavior is very bad and negative selfesteem. There is a significant relationship between self-esteem and smoking behavior at student health S1.