Background: Global Asthma Report 2011 describes for about 235 million people worldwide suffer from Asthma. Asthma can cause a number of harmful changes in the lung and respiratory tract. The most important effects are on decreasing airway quality and decreasing lung elasticity. Asthma treatment efforts have been carried out in a curative stage with controlling drugs and relatives, but the success of asthma treatment is not determined by the drugs consumed alone but also must be supported from the side of promotive and preventive. This study aims to determine the effect of health promotion on asthma with leaflets and Buteyko breathing exercises on the lung function in people with asthma. Method: Quasi experimental with pre-test and post test with control group design performed on 40 asthma patients in Lung Department in PKU Muhammadiyah Gamping Hospital from January to April 2017. Respondents consisted of 20 respondents as intervention group and 20 respondents as control group. Results: The result of Wilcoxon analysis test of intervention group obtained P value <0.001. The mean value of PEFR in the intervention group during pre-test was 281.00 to 294.75 while the result of Paired T-Test test analysis on the control group obtained P value = 0.007. The mean value of PEFR in the control group at the pretest was 268.50 to 294.60. Result of Mann-Whitney test analysis of pre-test group of intervention and control obtained value P <0.001. Then in the group of post-test intervention and control obtained value P <0.001. Conclusion: Health promotion of asthma with leaflets and Buteyko breathing exercise has a significant influence on improving the lung function on people with asthma.