This study aims to analyze the influence of investment, labor force and education on economic growth on the island of Borneo. This is an empirical study with a quantitative approach. The data used in this research is secondary data from 4 Provinces in Borneo island in 2008-2016. The analysis model used is panel regression analysis with fixed effect model. The results of this study indicate that investment variables have a positive and significant impact on economic growth, workforce variable has a positive and significant impact on economic growth and education variables have a positive and significant impact on economic growth.