Determinants of economic inequality is affected by the economic and non economic factors such as the Human Development Index (HDI), GrossDomestic Product per capita (GDP Per Capita) and Population (POP). This study aims to determine the determinants of economic inequality in Yogyakarta in 2011-2017.This study is of quantitative research. the data used were in the form of cross-section tabulations from 5 district/municipalities in Yogyakarta Special Province and the time series during 2011-2017. The data were analyzed using panel data analysis with fixed effect model regression. All the research variables proved to simultaneously influence the determinants of income inequality. In partial, the variable of the human development index significantly and population positively affect the gini index, while the variable of the GDP per capita significantly and negatively affect the gini index.